Antitumor effects of dammarane-type saponins from steamed Notoginseng

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Minor dehydrogenated and cleavaged dammarane-type saponins from the steamed roots of Panax notoginseng.

Nine new minor dehydrogenated and cleavaged dammarane-type triterpenoid saponins, namely notoginsenosides ST6-ST14 (1-9) were isolated from the steamed roots of Panax notoginseng, together with 14 known ones. Among them, 5-7 and 21-22 were protopanaxadiol type and the left 18 compounds, including 1-4, 8-20, and 23 were protopanaxatriol type saponins. Their structures were identified by extensiv...

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Dammarane-type triterpene saponins from the flowers of Panax notoginseng.

Four new dammarane-type triterpene saponins named floranotoginsenosides A (1), B (2), C (3) and D (4), together with five known triterpene saponins, were isolated from the flowers of Panax notoginseng. Their structures were elucidated on the basis of spectral and chemical evidence.

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Determination of Panax notoginseng Saponins

The feasible, reliable and selective multi-template molecularly imprinted polymers (MT17 MIPs) based on SBA-15 (SBA-15@MT-MIPs) for the selective separation and determination of the 18 trace level of ginsenoside Rb1 (Rb1), ginsenoside Rg1 (Rg1) and notoginsenoside R1 (R1) (Panax 19 notoginseng saponins, PNS) from biological samples were developed. The polymers were 20 constructed by SBA-15 as s...

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[Anti-inflammatory effects of total saponins of Panax notoginseng].

AIM To study the anti-inflammatory effects of total saponins of Panax notoginseng (PnS). METHODS Rat air-pouch acute inflammatory model was established with s.c. carrageenan (Car, 25 mg.kg-1). The protein content in exudate was measured. Micro-acid titration assay and radioimmunoassay (RIA) were applied respectively to investigate effects of PnS on phospholipase A2 (PLA2) activity and dinopro...

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Six new dammarane-type triterpene saponins from the leaves of Panax ginseng.

Six new minor saponins, together with known ginsenosides, were isolated from the leaves of Panax ginseng. The new saponins were named as ginsenoside-Rh5, -Rh6, -Rh7 -Rh8, -Rh9 and -Rg7, and their structures were elucidated on the basis of chemical and physicochemical evidence to be as follows: ginsenoside-Rh5: 3beta,6alpha,12beta,24zeta-tetrahydroxy-dammar-20(22),25-diene 6-O-beta-D-glucopyrano...

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ژورنال

عنوان ژورنال: Pharmacognosy Magazine

سال: 2014

ISSN: 0973-1296

DOI: 10.4103/0973-1296.137372